Open Access

Pancreatic stellate cells: Key players in pancreatic health and diseases (Review)

  • Authors:
    • Zhengfeng Wang
    • Shi Dong
    • Wence Zhou
  • View Affiliations

  • Published online on: May 1, 2024     https://doi.org/10.3892/mmr.2024.13233
  • Article Number: 109
  • Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

As a pluripotent cell, activated pancreatic stellate cells (PSCs) can differentiate into various pancreatic parenchymal cells and participate in the secretion of extracellular matrix and the repair of pancreatic damage. Additionally, PSCs characteristics allow them to contribute to pancreatic inflammation and carcinogenesis. Moreover, a detailed study of the pathogenesis of activated PSCs in pancreatic disease can offer promise for the development of innovative therapeutic strategies and improved patient prognoses. Therefore, the present study review aimed to examine the involvement of activated PSCs in pancreatic diseases and elucidate the underlying mechanisms to provide a viable therapeutic strategy for the management of pancreas‑related diseases.
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July-2024
Volume 30 Issue 1

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Copy and paste a formatted citation
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Spandidos Publications style
Wang Z, Dong S and Zhou W: Pancreatic stellate cells: Key players in pancreatic health and diseases (Review). Mol Med Rep 30: 109, 2024
APA
Wang, Z., Dong, S., & Zhou, W. (2024). Pancreatic stellate cells: Key players in pancreatic health and diseases (Review). Molecular Medicine Reports, 30, 109. https://doi.org/10.3892/mmr.2024.13233
MLA
Wang, Z., Dong, S., Zhou, W."Pancreatic stellate cells: Key players in pancreatic health and diseases (Review)". Molecular Medicine Reports 30.1 (2024): 109.
Chicago
Wang, Z., Dong, S., Zhou, W."Pancreatic stellate cells: Key players in pancreatic health and diseases (Review)". Molecular Medicine Reports 30, no. 1 (2024): 109. https://doi.org/10.3892/mmr.2024.13233